Starting in May 2016, the ratio expression format for drug concentrations will no longer be permitted. This new development will apply to epinephrine, isoproterenol and neostigmine. Unaffected by this are the lidocaine and epinephrine combination solutions for local anesthesia.
The new labeling for epinephrine will only be displayed as the mass concentration format used in virtually every other medication. For example, epinephrine 1:1000 will now be labeled as 1 mg/mL, and for the 1:10,000 as 0.1 mg/mL. It is hoped that this change will decrease medication errors in the field and in the hospital. pdf See the explanation HERE. (159 KB)